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A controversial issue: Can mitochondria modulate cytosolic calcium and contraction of skeletal muscle fibers?
Mitochondria are characterized by a high capacity to accumulate calcium thanks to the electrochemical gradient created by the extrusion of protons in the respiratory chain. Thereby calcium can enter crossing the inner mitochondrial membrane via MCU complex, a high-capacity, low-affinity transport me...
Autores principales: | Reggiani, Carlo, Marcucci, Lorenzo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297197/ https://www.ncbi.nlm.nih.gov/pubmed/35849108 http://dx.doi.org/10.1085/jgp.202213167 |
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