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N-Terminal cysteine mediated backbone-side chain cyclization for chemically enhanced phage display

Phage display, an ingenious invention for evaluating peptide libraries, has been limited to natural peptides that are ribosomally assembled with proteinogenic amino acids. Recently, there has been growing interest in chemically modifying phage libraries to create nonnatural cyclic and multicyclic pe...

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Detalles Bibliográficos
Autores principales: Zheng, Mengmeng, Haeffner, Fredrik, Gao, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297441/
https://www.ncbi.nlm.nih.gov/pubmed/35919713
http://dx.doi.org/10.1039/d2sc03241d