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Hydroarylation of enamides enabled by HFIP via a hexafluoroisopropyl ether as iminium reservoir
Here we describe that HFIP greatly expands the scope with respect to both reaction partners of the Brønsted acid-catalyzed hydroarylation of enamides. The reaction is fast and practical and can be performed on the gram scale. A hexafluoroisopropyl ether intermediate was isolated from the reaction mi...
Autores principales: | Zeidan, Nicolas, Bicic, Sergiu, Mayer, Robert J., Lebœuf, David, Moran, Joseph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297520/ https://www.ncbi.nlm.nih.gov/pubmed/35919727 http://dx.doi.org/10.1039/d2sc02012b |
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