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Solution structure of a thrombin binding aptamer complex with a non-planar platinum(ii) compound
Thrombin Binding Aptamer (TBA) is a monomolecular well-defined two G-tetrad antiparallel G-quadruplex DNA that inhibits the activity of human α-thrombin. In this report, we synthesized a quasi-cross-shaped platinum(ii) compound (L′(2)LPt) with one cyclometalated and two carbene ligands. We found L′(...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297526/ https://www.ncbi.nlm.nih.gov/pubmed/35919711 http://dx.doi.org/10.1039/d2sc01196d |