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Solution structure of a thrombin binding aptamer complex with a non-planar platinum(ii) compound

Thrombin Binding Aptamer (TBA) is a monomolecular well-defined two G-tetrad antiparallel G-quadruplex DNA that inhibits the activity of human α-thrombin. In this report, we synthesized a quasi-cross-shaped platinum(ii) compound (L′(2)LPt) with one cyclometalated and two carbene ligands. We found L′(...

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Detalles Bibliográficos
Autores principales: Zhu, Bo-Chen, He, Juan, Xia, Xiao-Yu, Jiang, Jingxing, Liu, Wenting, Liu, Liu-Yi, Liang, Bing-Bing, Yao, Hua-Gang, Ke, Zhuofeng, Xia, Wei, Mao, Zong-Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297526/
https://www.ncbi.nlm.nih.gov/pubmed/35919711
http://dx.doi.org/10.1039/d2sc01196d