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Deep learning for de-convolution of Smad2 versus Smad3 binding sites

BACKGROUND: The transforming growth factor beta-1 (TGF β-1) cytokine exerts both pro-tumor and anti-tumor effects in carcinogenesis. An increasing body of literature suggests that TGF β-1 signaling outcome is partially dependent on the regulatory targets of downstream receptor-regulated Smad (R-Smad...

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Detalles Bibliográficos
Autores principales: Ng, Jeremy W.K., Ong, Esther H.Q., Tucker-Kellogg, Lisa, Tucker-Kellogg, Greg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297549/
https://www.ncbi.nlm.nih.gov/pubmed/35858839
http://dx.doi.org/10.1186/s12864-022-08565-x