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CircGPR137B/miR-4739/FTO feedback loop suppresses tumorigenesis and metastasis of hepatocellular carcinoma

BACKGROUND: Emerging evidence indicates that circular RNAs (circRNAs) and m(6)A RNA methylation participate in the pathogenesis and metastasis of multiple malignancies including hepatocellular carcinoma (HCC). However, it remains undocumented how circRNAs form a feedback loop with the m(6)A modifica...

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Detalles Bibliográficos
Autores principales: Liu, Lianyong, Gu, Mingjun, Ma, Junhua, Wang, Ying, Li, Miao, Wang, Hui, Yin, Xin, Li, Xiangqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297645/
https://www.ncbi.nlm.nih.gov/pubmed/35858900
http://dx.doi.org/10.1186/s12943-022-01619-4