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Type III-A CRISPR systems as a versatile gene knockdown technology

CRISPR-Cas systems are functionally diverse prokaryotic antiviral defense systems, which encompass six distinct types (I–VI) that each encode different effector Cas nucleases with distinct nucleic acid cleavage specificities. By harnessing the unique attributes of the various CRISPR-Cas systems, a r...

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Detalles Bibliográficos
Autores principales: Woodside, Walter T., Vantsev, Nikita, Catchpole, Ryan J., Garrett, Sandra C., Olson, Sara, Graveley, Brenton R., Terns, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297841/
https://www.ncbi.nlm.nih.gov/pubmed/35618430
http://dx.doi.org/10.1261/rna.079206.122