Antisense modulation of IL7R splicing to control sIL7R expression in human CD4(+) T cells

The interleukin 7 receptor (IL7R) is strongly associated with increased risk to develop multiple sclerosis (MS), an autoimmune disease of the central nervous system, and this association is likely driven by up-regulation of the soluble isoform of IL7R (sIL7R). Expression of sIL7R is determined by ex...

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Detalles Bibliográficos
Autores principales: Galarza-Muñoz, Gaddiel, Kennedy-Boone, Debbie, Schott, Geraldine, Bradrick, Shelton S., Garcia-Blanco, Mariano A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297843/
https://www.ncbi.nlm.nih.gov/pubmed/35613883
http://dx.doi.org/10.1261/rna.079137.122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297843/
https://www.ncbi.nlm.nih.gov/pubmed/35613883
http://dx.doi.org/10.1261/rna.079137.122

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