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The Road Less Taken: Less Appreciated Pathways for Manipulating CD8(+) T Cell Exhaustion
Exhausted CD8(+) T (Tex) cells are a distinct cell population that arise during persistent antigen exposure in the context of chronic infections and cancers. Although characterized by progressive loss of effector functions, high and sustained inhibitory receptor expression and distinct transcription...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297918/ https://www.ncbi.nlm.nih.gov/pubmed/35874734 http://dx.doi.org/10.3389/fimmu.2022.926714 |