Activation of the calcium sensing receptor increases claudin‐14 expression via a PLC ‐p38‐Sp1 pathway

Activation of the basolateral calcium sensing receptor (CaSR) in the renal tubular thick ascending limb (TAL) increases claudin‐14 expression, which reduces paracellular calcium (Ca(2+)) permeability, thus increasing urinary Ca(2+) excretion. However, the upstream signaling pathway contributing to a...

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Detalles Bibliográficos
Autores principales: Lee, Justin J., Alzamil, Jawad, Rehman, Saba, Pan, Wanling, Dimke, Henrik, Alexander, R. Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297942/
https://www.ncbi.nlm.nih.gov/pubmed/34694654
http://dx.doi.org/10.1096/fj.202002137RRR

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297942/
https://www.ncbi.nlm.nih.gov/pubmed/34694654
http://dx.doi.org/10.1096/fj.202002137RRR

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