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Fast and Efficient Postsynthetic DNA Labeling in Cells by Means of Strain‐Promoted Sydnone‐Alkyne Cycloadditions

Sydnones are highly stable mesoionic 1,3‐dipoles that react with cyclooctynes through strain‐promoted sydnone‐alkyne cycloaddition (SPSAC). Although sydnones have been shown to be valuable bioorthogonal chemical reporters for the labeling of proteins and complex glycans, nucleic acids have not yet b...

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Detalles Bibliográficos
Autores principales: Krell, Katja, Pfeuffer, Bastian, Rönicke, Franziska, Chinoy, Zoeisha S., Favre, Camille, Friscourt, Frédéric, Wagenknecht, Hans‐Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297951/
https://www.ncbi.nlm.nih.gov/pubmed/34633713
http://dx.doi.org/10.1002/chem.202103026