Coupling Interrupted Fischer and Multicomponent Joullié‐Ugi to Chase Chemical Diversity: from Batch to Sustainable Flow Synthesis of Peptidomimetics

The generation of peptidomimetic substructures for medicinal chemistry purposes requires effective and divergent synthetic methods. We present in this work an efficient flow process that allows quick modulation of reagents for Joullié‐Ugi multicomponent reaction, using spiroindolenines as core motif...

Descripción completa

Detalles Bibliográficos
Autores principales: Alfano, Antonella Ilenia, Buommino, Elisabetta, Ferraro, Maria Grazia, Irace, Carlo, Zampella, Angela, Lange, Heiko, Brindisi, Margherita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297956/
https://www.ncbi.nlm.nih.gov/pubmed/34585536
http://dx.doi.org/10.1002/cmdc.202100474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297956/
https://www.ncbi.nlm.nih.gov/pubmed/34585536
http://dx.doi.org/10.1002/cmdc.202100474

Ejemplares similares