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Systematic Evaluation of Fluorination as Modification for Peptide‐Based Fusion Inhibitors against HIV‐1 Infection
With the emergence of novel viruses, the development of new antivirals is more urgent than ever. A key step in human immunodeficiency virus type 1 (HIV‐1) infection is six‐helix bundle formation within the envelope protein subunit gp41. Selective disruption of bundle formation by peptides has been s...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297971/ https://www.ncbi.nlm.nih.gov/pubmed/34605595 http://dx.doi.org/10.1002/cbic.202100417 |