Visible‐Light Removable Photocaging Groups Accepted by MjMAT Variant: Structural Basis and Compatibility with DNA and RNA Methyltransferases

Methylation and demethylation of DNA, RNA and proteins constitutes a major regulatory mechanism in epigenetic processes. Investigations would benefit from the ability to install photo‐cleavable groups at methyltransferase target sites that block interactions with reader proteins until removed by non...

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Detalles Bibliográficos
Autores principales: Peters, Aileen, Herrmann, Eric, Cornelissen, Nicolas V., Klöcker, Nils, Kümmel, Daniel, Rentmeister, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298006/
https://www.ncbi.nlm.nih.gov/pubmed/34606675
http://dx.doi.org/10.1002/cbic.202100437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298006/
https://www.ncbi.nlm.nih.gov/pubmed/34606675
http://dx.doi.org/10.1002/cbic.202100437

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