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Visible‐Light Removable Photocaging Groups Accepted by MjMAT Variant: Structural Basis and Compatibility with DNA and RNA Methyltransferases
Methylation and demethylation of DNA, RNA and proteins constitutes a major regulatory mechanism in epigenetic processes. Investigations would benefit from the ability to install photo‐cleavable groups at methyltransferase target sites that block interactions with reader proteins until removed by non...
Autores principales: | Peters, Aileen, Herrmann, Eric, Cornelissen, Nicolas V., Klöcker, Nils, Kümmel, Daniel, Rentmeister, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298006/ https://www.ncbi.nlm.nih.gov/pubmed/34606675 http://dx.doi.org/10.1002/cbic.202100437 |
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