Consensus Virtual Screening Identified [1,2,4]Triazolo[1,5‐b]isoquinolines As MELK Inhibitor Chemotypes

Maternal Embryonic Leucine‐zipper Kinase (MELK) is a current oncotarget involved in a diverse range of human cancers, with the usage of MELK inhibitors being explored clinically. Here, we aimed to discover new MELK inhibitor chemotypes from our in‐house compound library with a consensus‐based virtua...

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Detalles Bibliográficos
Autores principales: Rácz, Anita, Palkó, Roberta, Csányi, Dorottya, Riedl, Zsuzsanna, Bajusz, Dávid, Keserű, György M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298037/
https://www.ncbi.nlm.nih.gov/pubmed/34632716
http://dx.doi.org/10.1002/cmdc.202100569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298037/
https://www.ncbi.nlm.nih.gov/pubmed/34632716
http://dx.doi.org/10.1002/cmdc.202100569

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