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Saliva as a sampling matrix for therapeutic drug monitoring of gentamicin in neonates: A prospective population pharmacokinetic and simulation study

AIMS: Therapeutic drug monitoring (TDM) of gentamicin in neonates is recommended for safe and effective dosing and is currently performed by plasma sampling, which is an invasive and painful procedure. In this study, feasibility of a non‐invasive gentamicin TDM strategy using saliva was investigated...

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Detalles Bibliográficos
Autores principales: Samb, Amadou, Kruizinga, Matthijs, Tallahi, Younes, van Esdonk, Michiel, van Heel, Willemijn, Driessen, Gertjan, Bijleveld, Yuma, Stuurman, Rik, Cohen, Adam, van Kaam, Anton, de Haan, Timo R, Mathôt, Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298055/
https://www.ncbi.nlm.nih.gov/pubmed/34625981
http://dx.doi.org/10.1111/bcp.15105