Control of hippocampal prothrombin kringle‐2 (pKr‐2) expression reduces neurotoxic symptoms in five familial Alzheimer's disease mice

BACKGROUND AND PURPOSE: There is a scarcity of information regarding the role of prothrombin kringle‐2 (pKr‐2), which can be generated by active thrombin, in hippocampal neurodegeneration and Alzheimer's disease (AD). EXPERIMENTAL APPROACH: To assess the role of pKr‐2 in association with the ne...

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Detalles Bibliográficos
Autores principales: Kim, Sehwan, Moon, Gyeong Joon, Kim, Hyung Jun, Kim, Do‐Geun, Kim, Jaekwang, Nam, Youngpyo, Sharma, Chanchal, Leem, Eunju, Lee, Shinrye, Kim, Kyu‐Sung, Ha, Chang Man, McLean, Catriona, Jin, Byung Kwan, Shin, Won‐Ho, Kim, Dong Woon, Oh, Yong‐Seok, Hong, Chang‐Won, Kim, Sang Ryong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298060/
https://www.ncbi.nlm.nih.gov/pubmed/34524687
http://dx.doi.org/10.1111/bph.15681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298060/
https://www.ncbi.nlm.nih.gov/pubmed/34524687
http://dx.doi.org/10.1111/bph.15681

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