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Orthogonal Peptide‐Templated Labeling Elucidates Lateral ET(A)R/ET(B)R Proximity and Reveals Altered Downstream Signaling

Fine‐tuning of G protein‐coupled receptor (GPCR) signaling is important to maintain cellular homeostasis. Recent studies demonstrated that lateral GPCR interactions in the cell membrane can impact signaling profiles. Here, we report on a one‐step labeling method of multiple membrane‐embedded GPCRs....

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Detalles Bibliográficos
Autores principales: Wolf, Philipp, Mohr, Alexander, Gavins, Georgina, Behr, Victoria, Mörl, Karin, Seitz, Oliver, Beck‐Sickinger, Annette G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298254/
https://www.ncbi.nlm.nih.gov/pubmed/34699123
http://dx.doi.org/10.1002/cbic.202100340