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An Immunomodulatory Peptide Dendrimer Inspired from Glatiramer Acetate

Glatiramer acetate (GA) is a random polypeptide drug used to treat multiple sclerosis (MS), a chronic autoimmune disease. With the aim of identifying a precisely defined alternative to GA, we synthesized a library of peptide dendrimers with an amino acid composition similar to GA. We then challenged...

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Detalles Bibliográficos
Autores principales: Erzina, Dina, Capecchi, Alice, Javor, Sacha, Reymond, Jean‐Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298260/
https://www.ncbi.nlm.nih.gov/pubmed/34618395
http://dx.doi.org/10.1002/anie.202113562