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Olanzapine Promotes the Occurrence of Metabolic Disorders in Conditional TCF7L2-Knockout Mice

Objectives: Schizophrenia (SCZ) patients display higher incidence of metabolic syndrome (MetS) and comorbidity of type II diabetes. Both atypical antipsychotics and genetic variants are believed to predispose the patients with the risk, but their interplay remains largely unknown. TCF7L2 is one of t...

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Detalles Bibliográficos
Autores principales: Yang, Ye, Shen, Manjun, Li, Li, Long, Yujun, Wang, Lu, Lang, Bing, Wu, Renrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298277/
https://www.ncbi.nlm.nih.gov/pubmed/35874808
http://dx.doi.org/10.3389/fcell.2022.890472