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Large‐scale provocation studies identify maladaptive responses to ubiquitous aeroallergens as a correlate of severe allergic rhinoconjunctivitis and asthma

BACKGROUND: Allergic asthma (AA) and allergic rhinoconjunctivitis (ARC) are common comorbid environmentally triggered diseases. We hypothesized that severe AA/ARC reflects a maladaptive or unrestrained response to ubiquitous aeroallergens. METHODS: We performed provocation studies wherein six separa...

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Detalles Bibliográficos
Autores principales: Smith, Alisha M., Ramirez, Robert M., Harper, Nathan, Jimenez, Fabio, Branum, Anne P., Meunier, Justin A., Pandranki, Lavanya, Carrillo, Andrew, Winter, Caitlyn, Winter, Lauryn, Rather, Cynthia G., Ramirez, Daniel A., Andrews, Charles P., Restrepo, Marcos I., Maselli, Diego J., Pugh, Jacqueline A., Clark, Robert A., Lee, Grace C., Moreira, Alvaro G., Manoharan, Muthu Saravanan, Okulicz, Jason F., Jacobs, Robert L., Ahuja, Sunil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298287/
https://www.ncbi.nlm.nih.gov/pubmed/34606106
http://dx.doi.org/10.1111/all.15124