Optimal adaptive allocation using deep reinforcement learning in a dose‐response study

Estimation of the dose‐response curve for efficacy and subsequent selection of an appropriate dose in phase II trials are important processes in drug development. Various methods have been investigated to estimate dose‐response curves. Generally, these methods are used with equal allocation of subje...

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Detalles Bibliográficos
Autores principales: Matsuura, Kentaro, Honda, Junya, El Hanafi, Imad, Sozu, Takashi, Sakamaki, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298337/
https://www.ncbi.nlm.nih.gov/pubmed/34747043
http://dx.doi.org/10.1002/sim.9247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298337/
https://www.ncbi.nlm.nih.gov/pubmed/34747043
http://dx.doi.org/10.1002/sim.9247

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