Design, Synthesis and Structural Analysis of Glucocerebrosidase Imaging Agents

Gaucher disease (GD) is a lysosomal storage disorder caused by inherited deficiencies in β‐glucocerebrosidase (GBA). Current treatments require rapid disease diagnosis and a means of monitoring therapeutic efficacy, both of which may be supported by the use of GBA‐targeting activity‐based probes (AB...

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Detalles Bibliográficos
Autores principales: Rowland, Rhianna J., Chen, Yurong, Breen, Imogen, Wu, Liang, Offen, Wendy A., Beenakker, Thomas J., Su, Qin, van den Nieuwendijk, Adrianus M. C. H., Aerts, Johannes M. F. G., Artola, Marta, Overkleeft, Herman S., Davies, Gideon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298352/
https://www.ncbi.nlm.nih.gov/pubmed/34570911
http://dx.doi.org/10.1002/chem.202102359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298352/
https://www.ncbi.nlm.nih.gov/pubmed/34570911
http://dx.doi.org/10.1002/chem.202102359

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