Identification of a novel compound that simultaneously impairs the ubiquitin-proteasome system and autophagy

The ubiquitin-proteasome system (UPS) and macroautophagy/autophagy are the main proteolytic systems in eukaryotic cells for preserving protein homeostasis, i.e., proteostasis. By facilitating the timely destruction of aberrant proteins, these complementary pathways keep the intracellular environment...

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Detalles Bibliográficos
Autores principales: Giovannucci, Tatiana A., Salomons, Florian A., Stoy, Henriette, Herzog, Laura K., Xu, Shanshan, Qian, Weixing, Merino, Lara G., Gierisch, Maria E., Haraldsson, Martin, Lystad, Alf H., Uvell, Hanna, Simonsen, Anne, Gustavsson, Anna-Lena, Vallin, Michaela, Dantuma, Nico P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298443/
https://www.ncbi.nlm.nih.gov/pubmed/34740308
http://dx.doi.org/10.1080/15548627.2021.1988359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298443/
https://www.ncbi.nlm.nih.gov/pubmed/34740308
http://dx.doi.org/10.1080/15548627.2021.1988359

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