Haploinsufficient tumor suppressor PRP4K is negatively regulated during epithelial‐to‐mesenchymal transition

The pre‐mRNA processing factor 4 kinase (PRP4K, also known as PRPF4B) is an essential gene. However, reduced PRP4K expression is associated with aggressive breast and ovarian cancer phenotypes including taxane therapy resistance, increased cell migration and invasion in vitro, and cancer metastasis...

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Detalles Bibliográficos
Autores principales: Clarke, Livia E., Cook, Allyson, Mathavarajah, Sabateeshan, Bera, Amit, Salsman, Jayme, Habib, Elias, Van Iderstine, Carter, Bydoun, Moamen, Lewis, Stephen M., Dellaire, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298446/
https://www.ncbi.nlm.nih.gov/pubmed/34674320
http://dx.doi.org/10.1096/fj.202001063R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298446/
https://www.ncbi.nlm.nih.gov/pubmed/34674320
http://dx.doi.org/10.1096/fj.202001063R

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