CXCR4 as a novel target in immunology: moving away from typical antagonists

CXCR4 has been a target of interest in drug discovery for numerous years. However, so far, most if not all studies focused on finding antagonists of CXCR4 function. Recent studies demonstrate that targeting a minor allosteric pocket of CXCR4 induces an immunomodulating effect in immune cells express...

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Detalles Bibliográficos
Autores principales: Caspar, Birgit, Cocchiara, Pietro, Melet, Armelle, Van Emelen, Kristof, Van der Aa, Annegret, Milligan, Graeme, Herbeuval, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Newlands Press Ltd 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298491/
https://www.ncbi.nlm.nih.gov/pubmed/35875591
http://dx.doi.org/10.4155/fdd-2022-0007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298491/
https://www.ncbi.nlm.nih.gov/pubmed/35875591
http://dx.doi.org/10.4155/fdd-2022-0007

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