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CXCR4 as a novel target in immunology: moving away from typical antagonists

CXCR4 has been a target of interest in drug discovery for numerous years. However, so far, most if not all studies focused on finding antagonists of CXCR4 function. Recent studies demonstrate that targeting a minor allosteric pocket of CXCR4 induces an immunomodulating effect in immune cells express...

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Detalles Bibliográficos
Autores principales:	Caspar, Birgit, Cocchiara, Pietro, Melet, Armelle, Van Emelen, Kristof, Van der Aa, Annegret, Milligan, Graeme, Herbeuval, Jean-Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Newlands Press Ltd 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298491/ https://www.ncbi.nlm.nih.gov/pubmed/35875591 http://dx.doi.org/10.4155/fdd-2022-0007

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