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[(68)Ga]Ga-DOTA-Siglec-9 Detects Pharmacodynamic Changes of FAP-Targeted IL2 Variant Immunotherapy in B16-FAP Melanoma Mice

Vascular adhesion protein-1 (VAP-1) is an inflammation-inducible adhesion molecule, which supports contact between leukocytes and inflamed endothelium. There is evidence that VAP-1 is involved in the recruitment of leukocytes to melanoma tumors. Interleukin-2 (IL-2)-based immunotherapy is an efficie...

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Detalles Bibliográficos
Autores principales: Viitanen, Riikka, Virtanen, Helena, Liljenbäck, Heidi, Moisio, Olli, Li, Xiang-Guo, Nicolini, Valeria, Richard, Marine, Klein, Christian, Nayak, Tapan, Jalkanen, Sirpa, Roivainen, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298541/
https://www.ncbi.nlm.nih.gov/pubmed/35874707
http://dx.doi.org/10.3389/fimmu.2022.901693