Pyruvate Supports RET-Dependent Mitochondrial ROS Production to Control Mycobacterium avium Infection in Human Primary Macrophages

Macrophages deploy a variety of antimicrobial programs to contain mycobacterial infection. Upon activation, they undergo extensive metabolic reprogramming to meet an increase in energy demand, but also to support immune effector functions such as secretion of cytokines and antimicrobial activities....

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Detalles Bibliográficos
Autores principales: Røst, Lisa Marie, Louet, Claire, Bruheim, Per, Flo, Trude Helen, Gidon, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298545/
https://www.ncbi.nlm.nih.gov/pubmed/35874747
http://dx.doi.org/10.3389/fimmu.2022.891475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298545/
https://www.ncbi.nlm.nih.gov/pubmed/35874747
http://dx.doi.org/10.3389/fimmu.2022.891475

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