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A rapid LC-MS/MS method for simultaneous determination of quetiapine and duloxetine in rat plasma and its application to pharmacokinetic interaction study

Combinations of new antidepressants like duloxetine and second-generation antipsychotics like quetiapine are used in clinical treatment of major depressive disorder, as well as in forensic toxicology scenarios. The drug–drug interaction (DDI) between quetiapine and duloxetine is worthy of attention...

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Detalles Bibliográficos
Autores principales: Chen, Xiujuan, Liang, Chen, Cui, Lijun, Le, Jian, Qian, Zheyuan, Zhang, Runsheng, Hong, Zhanying, Chai, Yifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taiwan Food and Drug Administration 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298631/
https://www.ncbi.nlm.nih.gov/pubmed/30648587
http://dx.doi.org/10.1016/j.jfda.2018.07.003