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Stable Isotope Phosphate Labelling of Diverse Metabolites is Enabled by a Family of (18)O‐Phosphoramidites

Stable isotope labelling is state‐of‐the‐art in quantitative mass spectrometry, yet often accessing the required standards is cumbersome and very expensive. Here, a unifying synthetic concept for (18)O‐labelled phosphates is presented, based on a family of modified (18)O(2)‐phosphoramidite reagents....

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Detalles Bibliográficos
Autores principales: Haas, Thomas M., Mundinger, Stephan, Qiu, Danye, Jork, Nikolaus, Ritter, Kevin, Dürr‐Mayer, Tobias, Ripp, Alexander, Saiardi, Adolfo, Schaaf, Gabriel, Jessen, Henning J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298905/
https://www.ncbi.nlm.nih.gov/pubmed/34734451
http://dx.doi.org/10.1002/anie.202112457