G2019S LRRK2 Mutation Enhances MPP(+)-Induced Inflammation of Human Induced Pluripotent Stem Cells-Differentiated Dopaminergic Neurons

Induced pluripotent stem cells (iPSCs) offer an unprecedented opportunity to mimic human diseases of related cell types, but it is unclear whether they can successfully mimic age-related diseases such as Parkinson’s disease (PD). We generated iPSCs lines from three patients with familial PD associat...

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Detalles Bibliográficos
Autores principales: Chen, Ying, Yin, Qing, Cheng, Xiao-Yu, Zhang, Jin-Ru, Jin, Hong, Li, Kai, Mao, Cheng-Jie, Wang, Fen, Bei, Hong-Zhe, Liu, Chun-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298923/
https://www.ncbi.nlm.nih.gov/pubmed/35873822
http://dx.doi.org/10.3389/fnins.2022.947927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298923/
https://www.ncbi.nlm.nih.gov/pubmed/35873822
http://dx.doi.org/10.3389/fnins.2022.947927

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