Druggable Allosteric Sites in β‐Propeller Lectins

Carbohydrate‐binding proteins (lectins) are auspicious targets in drug discovery to combat antimicrobial resistance; however, their non‐carbohydrate drug‐like inhibitors are still unavailable. Here, we present a druggable pocket in a β‐propeller lectin BambL from Burkholderia ambifaria as a potentia...

Descripción completa

Detalles Bibliográficos
Autores principales: Shanina, Elena, Kuhaudomlarp, Sakonwan, Lal, Kanhaya, Seeberger, Peter H., Imberty, Anne, Rademacher, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298952/
https://www.ncbi.nlm.nih.gov/pubmed/34713573
http://dx.doi.org/10.1002/anie.202109339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298952/
https://www.ncbi.nlm.nih.gov/pubmed/34713573
http://dx.doi.org/10.1002/anie.202109339

Ejemplares similares