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Druggable Allosteric Sites in β‐Propeller Lectins

Carbohydrate‐binding proteins (lectins) are auspicious targets in drug discovery to combat antimicrobial resistance; however, their non‐carbohydrate drug‐like inhibitors are still unavailable. Here, we present a druggable pocket in a β‐propeller lectin BambL from Burkholderia ambifaria as a potentia...

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Detalles Bibliográficos
Autores principales:	Shanina, Elena, Kuhaudomlarp, Sakonwan, Lal, Kanhaya, Seeberger, Peter H., Imberty, Anne, Rademacher, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298952/ https://www.ncbi.nlm.nih.gov/pubmed/34713573 http://dx.doi.org/10.1002/anie.202109339

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