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MSC-Derived Small Extracellular Vesicles Attenuate Autoimmune Dacryoadenitis by Promoting M2 Macrophage Polarization and Inducing Tregs via miR-100-5p

BACKGROUND: Mesenchymal stem cell-derived small extracellular vesicles (MSC-sEVs) have been increasingly proved as promising immunomodulators against some autoimmune disorders. However, the possible effect and the underlying mechanism of MSC-sEVs in autoimmune dry eye have been rarely studied. METHO...

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Detalles Bibliográficos
Autores principales: Li, Na, Gao, Zhiqi, Zhao, Lu, Du, Bei, Ma, Binyun, Nian, Hong, Wei, Ruihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298967/
https://www.ncbi.nlm.nih.gov/pubmed/35874782
http://dx.doi.org/10.3389/fimmu.2022.888949