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Tongluo Yishen Decoction Ameliorates Renal Fibrosis via NLRP3-Mediated Pyroptosis In Vivo and In Vitro

Purpose: In this study, we investigated the mechanism of Tongluo Yishen (TLYS) decoction in more detail, from the perspective of pyroptosis in the unilateral ureteral ligation (UUO) model and the hypoxia-induced renal tubular epithelial (NRK-52E) cell. Method: The UUO model was used, and after 14 da...

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Detalles Bibliográficos
Autores principales: Jia, Qi, Zhang, Xiaoyu, Hao, Gaimei, Zhao, Yun, Lowe, Scott, Han, Lin, Qin, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298980/
https://www.ncbi.nlm.nih.gov/pubmed/35873572
http://dx.doi.org/10.3389/fphar.2022.936853