PDGFRα‐lineage origin directs monocytes to trafficking proficiency to support peripheral immunity

Multiple embryonic precursors give rise to leukocytes in adults while the lineage‐based functional impacts are underappreciated. Mesodermal precursors expressing PDGFRα appear transiently during E7.5‐8.5 descend to a subset of Lin(–)Sca1(+)Kit(+) hematopoietic progenitors found in adult BM. By analy...

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Detalles Bibliográficos
Autores principales: Li, Yu‐Tung, Yamazaki, Sho, Takaki, Eiichi, Ouchi, Yuya, Kitayama, Tomomi, Tamai, Katsuto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Innate immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299050/
https://www.ncbi.nlm.nih.gov/pubmed/34708880
http://dx.doi.org/10.1002/eji.202149479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299050/
https://www.ncbi.nlm.nih.gov/pubmed/34708880
http://dx.doi.org/10.1002/eji.202149479

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