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NKG7 Enhances CD8+ T Cell Synapse Efficiency to Limit Inflammation

Cytotoxic lymphocytes are essential for anti-tumor immunity, and for effective responses to cancer immunotherapy. Natural killer cell granule protein 7 (NKG7) is expressed at high levels in cytotoxic lymphocytes infiltrating tumors from patients treated with immunotherapy, but until recently, the ro...

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Detalles Bibliográficos
Autores principales: Lelliott, Emily J., Ramsbottom, Kelly M., Dowling, Mark R., Shembrey, Carolyn, Noori, Tahereh, Kearney, Conor J., Michie, Jessica, Parish, Ian A., Jordan, Margaret A., Baxter, Alan G., Young, Neil D., Brennan, Amelia J., Oliaro, Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299089/
https://www.ncbi.nlm.nih.gov/pubmed/35874669
http://dx.doi.org/10.3389/fimmu.2022.931630