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Site‐Selective Pd‐Catalyzed C(sp(3))−H Arylation of Heteroaromatic Ketones
A ligand‐controlled site‐selective C(sp(3))−H arylation of heteroaromatic ketones has been developed using Pd catalysis. The reaction occurred selectively at the α‐ or β‐position of the ketone side‐chain. The switch from α‐ to β‐arylation was realized by addition of a pyridone ligand. The α‐arylatio...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299137/ https://www.ncbi.nlm.nih.gov/pubmed/34761844 http://dx.doi.org/10.1002/chem.202103467 |