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Electrophilic Activation of [1.1.1]Propellane for the Synthesis of Nitrogen‐Substituted Bicyclo[1.1.1]pentanes

Strategies commonly used for the synthesis of functionalised bicyclo[1.1.1]pentanes (BCP) rely on the reaction of [1.1.1]propellane with anionic or radical intermediates. In contrast, electrophilic activation has remained a considerable challenge due to the facile decomposition of BCP cations, which...

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Detalles Bibliográficos
Autores principales: Livesley, Sarah, Sterling, Alistair J., Robertson, Craig M., Goundry, William R. F., Morris, James A., Duarte, Fernanda, Aïssa, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299141/
https://www.ncbi.nlm.nih.gov/pubmed/34705316
http://dx.doi.org/10.1002/anie.202111291