Photocleavable Fluorescent Membrane Tension Probes: Fast Release with Spatiotemporal Control in Inner Leaflets of Plasma Membrane, Nuclear Envelope, and Secretory Pathway

Mechanosensitive flipper probes are attracting interest as fluorescent reporters of membrane order and tension in biological systems. We introduce PhotoFlippers, which contain a photocleavable linker and an ultralong tether between mechanophore and various targeting motifs. Upon irradiation, the ori...

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Detalles Bibliográficos
Autores principales: López‐Andarias, Javier, Eblighatian, Krikor, Pasquer, Quentin T. L., Assies, Lea, Sakai, Naomi, Hoogendoorn, Sascha, Matile, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299180/
https://www.ncbi.nlm.nih.gov/pubmed/34734671
http://dx.doi.org/10.1002/anie.202113163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299180/
https://www.ncbi.nlm.nih.gov/pubmed/34734671
http://dx.doi.org/10.1002/anie.202113163

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