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Photocleavable Fluorescent Membrane Tension Probes: Fast Release with Spatiotemporal Control in Inner Leaflets of Plasma Membrane, Nuclear Envelope, and Secretory Pathway
Mechanosensitive flipper probes are attracting interest as fluorescent reporters of membrane order and tension in biological systems. We introduce PhotoFlippers, which contain a photocleavable linker and an ultralong tether between mechanophore and various targeting motifs. Upon irradiation, the ori...
Autores principales: | López‐Andarias, Javier, Eblighatian, Krikor, Pasquer, Quentin T. L., Assies, Lea, Sakai, Naomi, Hoogendoorn, Sascha, Matile, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299180/ https://www.ncbi.nlm.nih.gov/pubmed/34734671 http://dx.doi.org/10.1002/anie.202113163 |
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