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Selective (1)H(α) NMR Methods Reveal Functionally Relevant Proline cis/trans Isomers in Intrinsically Disordered Proteins: Characterization of Minor Forms, Effects of Phosphorylation, and Occurrence in Proteome

It is important to identify proline cis/trans isomers that appear in several regulatory mechanisms of proteins, and to characterize minor species that are present due to the conformational heterogeneity in intrinsically disordered proteins (IDPs). To obtain residue level information on these mobile...

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Detalles Bibliográficos
Autores principales: Sebák, Fanni, Ecsédi, Péter, Bermel, Wolfgang, Luy, Burkhard, Nyitray, László, Bodor, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299183/
https://www.ncbi.nlm.nih.gov/pubmed/34585830
http://dx.doi.org/10.1002/anie.202108361