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Systematic review reveals multiple sexually antagonistic polymorphisms affecting human disease and complex traits
An evolutionary model for sex differences in disease risk posits that alleles conferring higher risk in one sex may be protective in the other. These sexually antagonistic (SA) alleles are predicted to be maintained at frequencies higher than expected under purifying selection against unconditionall...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299215/ https://www.ncbi.nlm.nih.gov/pubmed/34723381 http://dx.doi.org/10.1111/evo.14394 |