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Systematic review reveals multiple sexually antagonistic polymorphisms affecting human disease and complex traits

An evolutionary model for sex differences in disease risk posits that alleles conferring higher risk in one sex may be protective in the other. These sexually antagonistic (SA) alleles are predicted to be maintained at frequencies higher than expected under purifying selection against unconditionall...

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Detalles Bibliográficos
Autores principales: Harper, Jon Alexander, Janicke, Tim, Morrow, Edward H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299215/
https://www.ncbi.nlm.nih.gov/pubmed/34723381
http://dx.doi.org/10.1111/evo.14394