ERα and ERβ Homodimers in the Same Cellular Context Regulate Distinct Transcriptomes and Functions

The two estrogen receptors ERα and ERβ are nuclear receptors that bind estrogen (E2) and function as ligand-inducible transcription factors. They are homologues and can form dimers with each other and bind to the same estrogen-response element motifs in the DNA. ERα drives breast cancer growth where...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Dandan, He, Huan, Indukuri, Rajitha, Huang, Zhiqiang, Stepanauskaite, Lina, Sinha, Indranil, Haldosén, Lars-Arne, Zhao, Chunyan, Williams, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299245/
https://www.ncbi.nlm.nih.gov/pubmed/35872983
http://dx.doi.org/10.3389/fendo.2022.930227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299245/
https://www.ncbi.nlm.nih.gov/pubmed/35872983
http://dx.doi.org/10.3389/fendo.2022.930227

Ejemplares similares