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Enzymes flying under the radar: Cryptic METTL3 can persist in knockout cells
The presence of m(6)A in mRNA of METTL3 knockout cells has long been a point of confusion. In this issue of PLOS Biology, Poh and colleagues reveal alternatively spliced, catalytically active METTL3 isoforms that persist in cells previously thought to lack the enzyme.
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299351/ https://www.ncbi.nlm.nih.gov/pubmed/35857761 http://dx.doi.org/10.1371/journal.pbio.3001717 |