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Therapeutic vs. Suprapharmacological Metformin Concentrations: Different Effects on Energy Metabolism and Mitochondrial Function in Skeletal Muscle Cells in vitro

Metformin is an oral antidiabetic agent that has been widely used in clinical practice for over 60 years, and is currently the most prescribed antidiabetic drug worldwide. However, the molecular mechanisms of metformin action in different tissues are still not completely understood. Although metform...

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Detalles Bibliográficos
Autores principales: Pavlovic, Kasja, Krako Jakovljevic, Nina, Isakovic, Andjelka M., Ivanovic, Tijana, Markovic, Ivanka, Lalic, Nebojsa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299382/
https://www.ncbi.nlm.nih.gov/pubmed/35873556
http://dx.doi.org/10.3389/fphar.2022.930308