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A Functional Interaction Between Y674-R685 Region of the SARS-CoV-2 Spike Protein and the Human α7 Nicotinic Receptor

The α7 nicotinic acetylcholine receptor (nAChR) is present in neuronal and non-neuronal cells and has anti-inflammatory actions. Molecular dynamics simulations suggested that α7 nAChR interacts with a region of the SARS-CoV-2 spike protein (S), and a potential contribution of nAChRs to COVID-19 path...

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Detalles Bibliográficos
Autores principales: Chrestia, Juan Facundo, Oliveira, Ana Sofia, Mulholland, Adrian J., Gallagher, Timothy, Bermúdez, Isabel, Bouzat, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299415/
https://www.ncbi.nlm.nih.gov/pubmed/35859025
http://dx.doi.org/10.1007/s12035-022-02947-8